Recombinant Human HDAC3 Protein, GST-tagged

• Cat.No.: HDAC3-94H
• Product Overview: Human recombinant HDAC3 (Full length) (residues 1-428; Genbank Accession #NM_003883; MW = 49.7 kDa) expressed in insect cells with a C-terminal His-fusion tag complexed with human recombinant NCOR2 (residues 395-489; Genebank Accession # NM_006312; MW= 38

Specification

• Source: Insect cell
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCl pH 7.5, 500 mM NaCl, 10% glycerol (w/v)
• Molecular Mass: 49.7/38.53 kDa
• Purity: >95% by SDS-PAGE
• Storage: Store at -80°C. Thaw quickly and store on ice before use. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HDAC3 histone deacetylase 3 [ Homo sapiens ]
• Official Symbol: HDAC3
• Synonyms: HDAC3; histone deacetylase 3; HD3; RPD3; RPD3 2; SMAP45; RPD3-2
• Gene ID: 8841
• mRNA Refseq: NM_003883
• Protein Refseq: NP_003874
• MIM: 605166
• UniProt ID: O15379
• Chromosome Location: 5q31.1-q31.2
• Pathway: BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Cell cycle, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem; Developmenta
• Function: DNA binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); chromatin binding; enzyme binding; histone deacetylase ac