Recombinant Human Heat Shock Factor Binding Protein 1

• Cat.No.: HSBP1-311H
• Product Overview: Recombinant Human HSBP1 protein was overexpressed in E.coli and purified to apparent homogeneity by using conventional column chromatography techniques (76 aa, 8.5 kDa).

Specification

• Cat. No.: HSBP1-311H
• Description: Heat shock factor binding protein 1 (HSBP1) is a 76 amino acid protein that binds to heat shock factor 1(HSF1), which is a transcription factor involved in the HS response. HSBP1 is nuclear-localized and interacts with the active trimeric state of HSF1 to negatively regulated HSF1 DNA-binding activity.
• Source: E.coli.
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM DTT, 50 mM NaCl, 20% glycerol.
• Molecular Weight: 8.5 kDa (76aa).
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequence: MAETDPKTVQ DLTSVVQTLL QQMQDKFQTM SDQIIGRIDD MSSRIDDLEK NIADLMTQAG VEELESENKI PATQKS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HSBP1
• Synonyms: HSBP1; heat shock factor binding protein 1; NPC-A-13; DKFZp686D1664; DKFZp686O24200; HSF1BP; Nasopharyngeal carcinoma-associated antigen 13.
• Gene ID: 3281
• mRNA Refseq: NM_001537.2
• Protein Refseq: NP_001528.1
• MIM: 604553
• UniProt ID: O75506
• Chromosome Location: 16q23.3
• Function: transcription corepressor activity.