Recombinant Human HELLS, GST-tagged

• Cat.No.: HELLS-13730H
• Product Overview: Recombinant Human HELLS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-348a.a.
• Description: This gene encodes a lymphoid-specific helicase. Other helicases function in processes involving DNA strand separation, including replication, repair, recombination, and transcription. This protein is thought to be involved with cellular proliferation and may play a role in leukemogenesis. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: HELLS helicase, lymphoid-specific [ Homo sapiens ]
• Official Symbol: HELLS
• Synonyms: HELLS; helicase, lymphoid-specific; lymphoid-specific helicase; LSH; Nbla10143; PASG; proliferation associated SNF2 like protein; SMARCA6; SWI/SNF2 related; matrix associated; actin dependent regulator of chromatin; subfamily A; member 6; proliferation-associated SNF2-like protein; SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6; SWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin, subfamily A, member 6; FLJ10339
• Gene ID: 3070
• mRNA Refseq: NM_018063
• Protein Refseq: NP_060533
• MIM: 603946
• UniProt ID: Q9NRZ9
• Chromosome Location: 10q24.2
• Pathway: Apoptosis, organism-specific biosystem
• Function: ATP binding; DNA binding; chromatin binding; helicase activity; hydrolase activity; nucleic acid binding; nucleotide binding