"HEMK1" Related Products

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Recombinant Human HEMK1 protein, GST-tagged

Cat.No.: HEMK1-186H
Product Overview: Recombinant Human HEMK1 fused with GST tag at N-terminal was expressed in Insect cells.
Description: HEMK1 belongs to the HemK methyltransferase family, members of which are found in genomes from bacteria to humans. HEMK1 methylates the glutamine residue in the GGQ motif of HMRF1L, a human mitochondrial release factor, and plays an important regulatory role in translation termination process.
Source: Insect cells
Species: Human
Tag : GST
Form: 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Molecular Mass: 65 kDa
Applications: Methyltransferase Assay
Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: HEMK1 HemK methyltransferase family member 1 [ Homo sapiens ]
Official Symbol: HEMK1
Synonyms: HEMK1; HemK methyltransferase family member 1; hemK methyltransferase family member 1; MTQ1; m.HsaHemKP; HEMK homolog 7kb; HEMK; FLJ22320;
Gene ID: 51409
mRNA Refseq: NM_016173
Protein Refseq: NP_057257
UniProt ID: Q9Y5R4
Chromosome Location: 3p21
Pathway: Histidine metabolism, organism-specific biosystem; Histidine metabolism, conserved biosystem; Tyrosine metabolism, organism-specific biosystem; Tyrosine metabolism, conserved biosystem;
Function: DNA binding; N-methyltransferase activity; protein methyltransferase activity; transferase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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