Recombinant Human HIST1H2AC Protein, GST-tagged

• Cat.No.: HIST1H2AC-4778H
• Product Overview: Human HIST1H2AC full-length ORF ( NP_003503.1, 1 a.a. - 130 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 40.5 kDa
• AA Sequence: MSGRGKQGGKARAKAKSRSSRAGLQ FPVGRVHRLLRKGNYAERVGAGAPV YLAAVLEYLTAEILELAGNAARDNK KTRIIPRHLQLAIRNDEELNKLLGR VTIAQGGVLPNIQAVLLPKKTESHH KAKGK
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HIST1H2AC histone cluster 1, H2ac [ Homo sapiens ]
• Official Symbol: HIST1H2AC
• Synonyms: HIST1H2AC; histone cluster 1, H2ac; H2A histone family, member L , H2AFL, histone 1, H2ac; histone H2A type 1-C; histone H2AC; histone H2A/l; histone 1, H2ac; H2A histone family, member L; H2A/l; H2AFL; dJ221C16.4; MGC99519
• Gene ID: 8334
• mRNA Refseq: NM_003512
• Protein Refseq: NP_003503
• MIM: 602794
• UniProt ID: Q93077