Recombinant Human Histone Deacetylase 11, GST-tagged

• Cat.No.: HDAC11-1589H
• Product Overview: Recombinant full length human HDAC11 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: HDAC11-1589H
• Description: HDAC11 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. HDAC11 belongs to class IV of the histone deacetylase family that localizes to the nucleus and is involved in regulating the expression of interleukin 10. HDAC11 expression is the highest in brain, heart, skeletal muscle, kidney and testis.
• Applications: HDAC Assay, Western Blot
• Molecular Weight: 66 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Human
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Purity: >75%
• Concentration: 0.1 ug/ul
• Specific Activity: 52 RLU/min/ng
• Sequences: Full length
• Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: Signaling events mediated by HDAC Class I; Signaling events mediated by HDAC Class II

Gene Information

• Gene Name: HDAC11 histone deacetylase 11 [ Homo sapiens ]
• Official Symbol: HDAC11
• Synonyms: HDAC11; histone deacetylase 11; HD11; FLJ22237; histone deacetylase 11; OTTHUMP00000160231; OTTHUMP00000197639; OTTHUMP00000197644; OTTHUMP00000197649; OTTHUMP00000208001; OTTHUMP00000209466; OTTHUMP00000226982
• Gene ID: 79885
• mRNA Refseq: NM_024827
• Protein Refseq: NP_079103
• MIM: 601241
• UniProt ID: Q96DB2
• Chromosome Location: 3p25
• Function: NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); histone deacetylase activity; histone deacetylase activity (H3-K16 specific); hydrolase activity; transcription factor binding