Recombinant Human HLA-DPA1, GST-tagged
Cat.No. : | HLA-DPA1-13816H |
Product Overview : | Recombinant Human HLA-DPA1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 32-224a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 [ Homo sapiens ] |
Official Symbol : | HLA-DPA1 |
Synonyms : | HLA-DPA1; major histocompatibility complex, class II, DP alpha 1; HLA DP1A; HLA class II histocompatibility antigen, DP alpha 1 chain; MHC class II DPA1; HLA-SB alpha chain; MHC class II antigen; MHC class II DP3-alpha; Primed lymphocyte test-1; MHC class II HLA-DPA1 antigen; HLA class II histocompatibility antigen, DP alpha chain; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DP1A; |
Gene ID : | 3113 |
mRNA Refseq : | NM_001242524 |
Protein Refseq : | NP_001229453 |
MIM : | 142880 |
UniProt ID : | P20036 |
Chromosome Location : | 6p21.3 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; |
Function : | MHC class II receptor activity; |
Products Types
◆ Recombinant Protein | ||
HLA-DPA1-4840H | Recombinant Human HLA-DPA1 Protein, GST-tagged | +Inquiry |
HLA-DPA1-5442Z | Recombinant Zebrafish HLA-DPA1 | +Inquiry |
HLA-DPA1-5290H | Recombinant Human HLA-DPA1 protein, His-tagged | +Inquiry |
HLA-DPA1-3427H | Recombinant Human HLA-DPA1 protein, His-tagged | +Inquiry |
◆ Lysates | ||
HLA-DPA1-5506HCL | Recombinant Human HLA 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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