Recombinant Human HOXD13 cell lysate

• Cat.No.: HOXD13-813HCL

Specification

• Description: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5 end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly.
• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: HOXD13 homeobox D13 [ Homo sapiens ]
• Official Symbol: HOXD13
• Synonyms: BDE; SPD; BDSD; HOX4I; homeobox protein Hox-D13; homeo box 4I; homeo box D13; homeobox protein Hox-4I
• Gene ID: 3239
• mRNA Refseq: NM_000523
• Protein Refseq: NP_000514
• MIM: 142989
• UniProt ID: P35453
• Chromosome Location: 2q31.1
• Function: DNA binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity