Recombinant Human HPS4, His-tagged

• Cat.No.: HPS4-13927H
• Product Overview: Recombinant Human HPS4 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-350a.a.
• Description: This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: HPS4 Hermansky-Pudlak syndrome 4 [ Homo sapiens ]
• Official Symbol: HPS4
• Synonyms: HPS4; Hermansky-Pudlak syndrome 4; Hermansky-Pudlak syndrome 4 protein; KIAA1667; LE; light-ear protein homolog; bK1048E9.4; bK1048E9.5
• Gene ID: 89781
• mRNA Refseq: NM_022081
• Protein Refseq: NP_071364
• MIM: 606682
• UniProt ID: Q9NQG7
• Chromosome Location: 22cen-q12.3
• Function: protein binding; protein dimerization activity; protein homodimerization activity