Recombinant Human HSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HSF1-3964H
• Product Overview: HSF1 MS Standard C13 and N15-labeled recombinant protein (NP_005517) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 57.1 kDa
• AA Sequence: MDLPVGPGAAGPSNVPAFLTKLWTL VSDPDTDALICWSPSGNSFHVFDQG QFAKEVLPKYFKHNNMASFVRQLNM YGFRKVVHIEQGGLVKPERDDTEFQ HPCFLRGQEQLLENIKRKVTSVSTL KSEDIKIRQDSVTKLLTDVQLMKGK QECMDSKLLAMKHENEALWREVASL RQKHAQQQKVVNKLIQFLISLVQSN RILGVKRKIPLMLNDSGSAHSMPKY SRQFSLEHVHGSGPYSAPSPAYSSS SLYAPDAVASSGPIISDITELAPAS PMASPGGSIDERPLSSSPLVRVKEE PPSPPQSPRVEEASPGRPSSVDTLL SPTALIDSILRESEPAPASVTALTD ARGHTDTEGRPPSPPPTSTPEKCLS VACLDKNELSDHLDAMDSNLDNLQT MLSSHGFSVDTSALLDLFSPSVTVP DMSLPDLDSSLASIQELLSPQEPPR PPEAENSSPDSGKQLVHYTAQPLFL LDPGSVDTGSNDLPVLFELGEGSYF SEGDGFAEDPTISLLTGSEPPKAKD PTVSTRTRPLEQKLISEEDLAANDI LDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HSF1 heat shock transcription factor 1 [ Homo sapiens (human) ]
• Official Symbol: HSF1
• Synonyms: HSF1; heat shock transcription factor 1; heat shock factor protein 1; HSTF1; HSF 1; HSTF 1
• Gene ID: 3297
• mRNA Refseq: NM_005526
• Protein Refseq: NP_005517
• MIM: 140580
• UniProt ID: Q00613