Recombinant Human HSPB7, His-tagged

• Cat.No.: HSPB7-2047H
• Product Overview: Recombinant human HSPB7 protein fused to His-tag was expressed inE.coliand purified by using conventional chromatography techniques. 20.7kDa (190aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: HSPB7 is a member of HSPB (Heat shock protein beta) family. The HSPB family is one of the more diverse families within the group of HSP families. Some members have chaperone-like activities and/or play a role in cytoskeletal stabilization. Some members also show a dynamic, stress-induced translocation to SC35 splicing speckles. HSPB7 constitutively localized to SC35 splicing speckles, driven by its N-terminus. Unlike HSPB1 and HSPB5, that chaperoned heat unfolded substrates and kept them folding competent, HSPB7 did not support refolding.
• Form: Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 200mM NaCl, 2mM DTT, 50% glycerol.
• Purity: > 85% by SDS - PAGE.
• Concentration: 0.25 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSHRTSSTFR AERSFHSSSS SSSSSTSSSA SRALPAQDPP MEKALSMFSD DFGSFMRPHS EPLAFPARPG GAGNIKTLGD AYEFAVDVRD FSPEDIIVTT SNNHIEVRAE KLAADGTVMN TFAHKCQLPE DVDPTSVTSA LREDGSLTIR ARRHPHTEHVQQTFRTEIKI.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) [ Homo sapiens ]
• Synonyms: heat shock 27kDa protein family, member 7 (cardiovascular); cvHSP; FLJ32733; DKFZp779D0968; HSPB7; heat shock protein beta-7; cardiovascular heat shock protein; heat shock 27kD protein family, member 7 (cardiovascular); Cardiovascular heat shock protein; cvHsp; HspB7
• Gene ID: 27129
• mRNA Refseq: NM_014424
• Protein Refseq: NP_055239
• MIM: 610692
• UniProt ID: Q9UBY9
• Chromosome Location: 1p36.23-p34.3
• Function: protein C-terminus binding; protein binding