Recombinant Human HTR3A Protein

• Cat.No.: HTR3A-5240H
• Product Overview: Human HTR3A full-length ORF (AAH02354.1) recombinant protein without tag.

Specification

• Description: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 55.3 kDa
• AA Sequence: MLLWVQQALLALLLPTLLAQGEARR SRNTTRPALLRLSDYLLTNYRKGVR PVRDWRKPTTVSIDVIVYAILNVDE KNQVLTTYIWYRQYWTDEFLQWNPE DFDNITKLSIPTDSIWVPDILINEF VDVGKSPNIPYVYIRHQGEVQNYKP LQVVTACSLDIYNFPFDVQNCSLTF TSWLHTIQDINISLWRLPEKVKSDR SVFMNQGEWELLGVLPYFREFSMES SNYYAEMKFYVVIRRRPLFYVVSLL LPSIFLMVMDIVGFYLPPNSGERVS FKITLLLGYSVFLIIVSDTLPATAI GTPLIGVYFVVCMALLVISLAETIF IVRLVHKQDLQQPVPAWLRHLVLER IAWLLCLREQSTSQRPPATSQATKT DDCSAMGNHCSHMGGPQDFEKSPRD RCSPPPPPREASLAVCGLLQELSSI RQFLEKRDEIREVARDWLRVGSVLD KLLFHIYLLAVLAYSITLVMLWSIW QYA
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic [ Homo sapiens ]
• Official Symbol: HTR3A
• Synonyms: HTR3A; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; 5 hydroxytryptamine (serotonin) receptor 3A , HTR3; 5-hydroxytryptamine receptor 3A; 5 HT3A; 5 HT3R; 5-HT3-A; serotonin receptor 3A; 5HT3 serotonin receptor; 5-hydroxytryptamine receptor 3; serotonin-gated ion channel receptor; HTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R
• Gene ID: 3359
• mRNA Refseq: NM_000869
• Protein Refseq: NP_000860
• MIM: 182139
• UniProt ID: P46098