Recombinant Human HTRA4, His-tagged

• Cat.No.: HTRA4-48H
• Product Overview: Recombinant human HTRA4 (159-376) protein was expressed in E. coli cells using an N-terminal His-tag.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 159-376 a.a.
• Description: HTRA1 is a serine protease with a conserved trypsin domain and a PDZ domain. As other related family members, HTRA4 may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. HrtA4 may contribute to shallow trophoblast invasion in preeclampsia and imply a potential application as a biomarker for this disorder.
• Form: 50mM Tris-HCl, pH 8.0, 300mM NaCl, 150mM imidazole and 10% glycerol.
• Molecular Mass: ~25 kDa
• Applications: Western Blot
• Storage: Store product at –70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1ug/ul

Gene Information

• Gene Name: HTRA4 HtrA serine peptidase 4 [ Homo sapiens ]
• Official Symbol: HTRA4
• Synonyms: HTRA4; HtrA serine peptidase 4; probable serine protease HTRA4; FLJ90724
• Gene ID: 203100
• mRNA Refseq: NM_153692
• Protein Refseq: NP_710159
• MIM: 610700
• UniProt ID: P83105
• Chromosome Location: 8p11.23
• Function: insulin-like growth factor binding; peptidase activity; serine-type endopeptidase activity