Recombinant Human HUS1 Protein, GST-tagged
Cat.No. : | HUS1-5225H |
Product Overview : | Human HUS1 full-length ORF ( AAH07013, 1 a.a. - 280 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 56.54 kDa |
AA Sequence : | MKFRAKIVDGACLNHFTRISNMIAK LAKTCTLRISPDKLNFILCDKLANG GVSMWCELEQENFFNEFQMEGVSAE NNEIYLELTSENLSRALKTAQNARA LKIKLTNKHFPCLTVSVELLSMSSS SRIVTHDIPIKVIPRKLWKDLQEPV VPDPDVSIYLPVLKTMKSVVEKMKN ISNHLVIEANLDGELNLKIETELVC VTTHFKDLGNPPLASESTHEDRNVE HMAEVHIDIRKLLQFLAGQQVNPTK ALCNIVNNKMVHFDLLHEDVSLQYF IPALS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | HUS1 HUS1 checkpoint homolog (S. pombe) [ Homo sapiens ] |
Official Symbol : | HUS1 |
Synonyms : | HUS1; HUS1 checkpoint homolog (S. pombe); HUS1 (S. pombe) checkpoint homolog; checkpoint protein HUS1; hus1+ like protein; hus1+-like protein; hHUS1; |
Gene ID : | 3364 |
mRNA Refseq : | NM_004507 |
Protein Refseq : | NP_004498 |
MIM : | 603760 |
UniProt ID : | O60921 |
Products Types
◆ Recombinant Protein | ||
HUS1-4386M | Recombinant Mouse HUS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Hus1-1201M | Recombinant Mouse Hus1 Protein, MYC/DDK-tagged | +Inquiry |
HUS1-7948M | Recombinant Mouse HUS1 Protein | +Inquiry |
HUS1-3364H | Recombinant Human HUS1, His-tagged | +Inquiry |
HUS1-29414TH | Recombinant Human HUS1, His-tagged | +Inquiry |
◆ Lysates | ||
HUS1-5327HCL | Recombinant Human HUS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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