Recombinant Human IDO2 protein, His-tagged
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Cat.No. : | IDO2-22H |
Product Overview : | Recombinant Human IDO2(15-420 aa) fused with His tag at N-terminal was expressed in E. coli. |
Description : | Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]). |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween- 20, 20% glycerol, 3 mM DTT and 150 mM imidazole. |
Molecular Mass : | 46 kDa |
AA Sequence : | MHHHHHHAHA MENSWTISKE YHIDEEVGFA LPNPQENLPD FYNDWMFIAK HLPDLIESGQ LRERVEKLNM LSIDHLTDHK SQRLARLVLG CITMAYVWGK GHGDVRKVLP RNIAVPYCQL SKKLELPPIL VYADCVLANW KKKDPNKPLT YENMDVLFSF RDGDCSKGFF LVSLLVEIAA ASAIKVIPTV FKAMQMQERD TLLKALLEIA SCLEKALQVF HQIHDHVNPK AFFSVLRIYL SGWKGNPQLS DGLVYEGFWE DPKEFAGGSA GQSSVFQCFD VLLGIQQTAG GGHAAQFLQD MRRYMPPAHR NFLCSLESNP SVREFVLSKG DAGLREAYDA CVKALVSLRS YHLQIVTKYI LIPASQQPKE NKTSEDPSKL EAKGTGGTDL MNFLKTVRST TE<br/>KSL LKEG |
Purity : | > 90% |
Applications : | Useful for studying enzyme kinetics, substrate specificity, and screening inhibitors. |
Storage : | At least 6 months at –80 centigrade. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%). |
Figure : |
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Gene Name : | IDO2 indoleamine 2,3-dioxygenase 2 [ Homo sapiens ] |
Official Symbol : | IDO2 |
Synonyms : | IDO2; indoleamine 2,3-dioxygenase 2; INDOL1, indoleamine pyrrole 2,3 dioxygenase like 1; IDO-2; indoleamine 2,3-dioxygenase-like 1 protein; indoleamine 2,3-dioxygenase-like protein 1; indoleamine-pyrrole 2,3 dioxygenase-like 1; indoleamine-pyrrole 2,3-dioxygenase-like protein 1; INDOL1; |
Gene ID : | 169355 |
mRNA Refseq : | NM_194294 |
Protein Refseq : | NP_919270 |
MIM : | 612129 |
UniProt ID : | Q6ZQW0 |
Chromosome Location : | 8p11.21 |
Pathway : | African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Tryptophan catabolism, organism-specific biosystem; Tryptophan metabolism, organism-specific biosystem; |
Function : | heme binding; indoleamine 2,3-dioxygenase activity; indoleamine 2,3-dioxygenase activity; metal ion binding; oxidoreductase activity; tryptophan 2,3-dioxygenase activity; |
◆ Recombinant Protein
IDO2-1420H | Recombinant Human IDO2 Protein (14-420 aa), His-tagged | +Inquiry |
Ido2-3475M | Recombinant Mouse Ido2 Protein, Myc/DDK-tagged | +Inquiry |
IDO2-23H | Recombinant Human IDO2 protein, MYC/DDK-tagged | +Inquiry |
IDO2-557H | Recombinant Human IDO2 Protein, His-tagged | +Inquiry |
Ido2-1176M | Recombinant Mouse Ido2 protein, His-tagged | +Inquiry |
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◆ Lysates
IDO2-5299HCL | Recombinant Human IDO2 293 Cell Lysate | +Inquiry |
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◆ Assay kits
Kit-1783 | Mouse IDO2 Inhibitor Screening Assay Kit | +Inquiry |
Kit-1759 | Human IDO2 Inhibitor Screening Assay Kit | +Inquiry |
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