| Description : |
This gene encodes a member of the sulfatase family of proteins. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. This enzyme is involved in the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
61.87 kDa |
| AA Sequence : |
MPPPRTGRGLLWLGLVLSSVCVALG SETQANSTTDALNVLLIIVDDLRPS LGCYGDKLVRSPNIDQLASHSLLFQ NAFAQQAVCAPSRVSFLTGRRPDTT RLYDFNSYWRVHAGNFSTIPQYFKE NGYVTMSVGKVFHPGISSNHTDDSP YSWSFPPYHPSSEKYENTKTCRGPD GELHANLLCPVDVLDVPEGTLPDKQ STEQAIQLLEKMKTSASPFFLAVGY HKPHIPFRYPKEFQKLYPLENITLA PDPEVPDGLPPVAYNPWMDIRQRED VQALNISVPYGPIPVDFQRKIRQSY FASVSYLDTQVGRLLSALDDLQLAN STIIAFTSDHGWALGEHGEWAKYSN FDVATHVPLIFYVPGRTASLPEAGE KLFPYLDPFDSASQLMEPGRQSMDL VELVSLFPTLAGLAGLQVPPRCPVP SFHVELCREGKNLLKHFRFRDLEED PYLPGNPRELIAYSQYPRPSDIPQW NSDKPSLKDIKIMGYSIRTIDYRYT VWVGFNPDEFLANFSDIHAGELYFV DSDPLQDHNMYNDSQGGDLFQLLMP TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
