Recombinant Human IKBKG, GST-tagged
Cat.No. : | IKBKG-195H |
Product Overview : | Recombinant human IKBKG (amino acid residues 2-418), fused with N-terminal GST, was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | NEMO (NFκB Essential Modifier) is the protypic member of a family of proteins that interact with Lys63-linked and linear polyubiquitin chains (Nanda et al.,2011). NEMO functions as a high affinity receptor for linear ubiquitin chains and a low affinity receptor for long lysine-linked ubiquitin chains. It is thought that this phenomenon could explain quantitatively distinct NF-κB activation patterns in response to numerous cell stimuli (Kensche et al., 2012). |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | 50 mM HEPES pH 7.5, 150 mM sodium chloride, 2 mM dithiothreitol, 10% glycerol |
Molecular Mass : | 74.9kDa |
Purity : | >85% by SDS-PAGE |
Storage : | 12 months at -70°C. Avoid multiple freeze/thaw cycles. |
Concentration : | 0.5 mg/ml |
Gene Name : | IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma [ Homo sapiens ] |
Official Symbol : | IKBKG |
Synonyms : | IKBKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; incontinentia pigmenti , IP1, IP2; NF-kappa-B essential modulator; FIP 3; FIP3; Fip3p; IKK gamma; NEMO; IKKG; IKKAP1; incontinentia pigmenti; IkB kinase gamma subunit; ikB kinase subunit gamma; NFkappaB essential modulator; NF-kappa-B essential modifier; I-kappa-B kinase subunit gamma; ikB kinase-associated protein 1; inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; FIP-3; AMCBX1; IKK-gamma; |
Gene ID : | 8517 |
mRNA Refseq : | NM_001099856 |
Protein Refseq : | NP_001093326 |
MIM : | 300248 |
UniProt ID : | Q9Y6K9 |
Chromosome Location : | Xq28 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; |
Function : | metal ion binding; protein binding; protein domain specific binding; signal transducer activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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