Recombinant Human IL12A&IL12B protein, His-Avi-tagged

• Cat.No.: IL12A&IL12B-460H
• Product Overview: Recombinant Human IL12 Protein is expressed from mammalian with a His Tag and Avi Tag at the C-terminal. It contains Ile23-Ser328(IL12B/P40)/Arg23-Ser219(P35/IL12A).

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Ile23-Ser328(IL12B/P40)/Arg23-Ser219(P35/IL12A)
• Description: Interleukin 12 (IL-12) is a pleiotropic cytokine that plays an essential role in Th1-type immune response against cancer, a condition where cells in a particular part of the body grow and reproduce uncontrollably.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 34.7(IL12B/P40) /25.5 (P35/IL12A) kDa.Due to glycosylation, the protein migrates to 45/40 KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.1 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL12A&IL12B
• Official Symbol: IL12A&IL12B
• Synonyms: CLMF; CLMF2; IL-12A; IL-12B; IL12; IL12 p70; IMD28; IMD29; NFSK; NKSF; NKSF1; NKSF2; P35
• Gene ID: 3592 & 3593
• mRNA Refseq: NM_000882.4 & NM_002187.3
• Protein Refseq: NP_000873.2 & NP_002178.2
• MIM: 161560 & 161561
• UniProt ID: P29459 & P29460