| Cat.No. : |
IL13RA1-48H
Optional Service: Optional requirements on this protein
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| Product Overview : |
Recombinant human IL13RA1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Description : |
IL13RA1, also known as Interleukin-13 receptor subunit alpha-1, is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. It is essential for allergen-induced airway hyperactivity and mucus hypersecretion. |
| Source : |
Insect cell |
| Species : |
Human |
| Tag : |
His |
| Form : |
Liquid. In Phosphate buffer saline (pH 7.4) |
| Molecular Mass : |
37.7kDa (328aa) 40-57kDa (SDS-PAGE under reducing conditions.) |
| AA Sequence : |
GGGGAAPTET QPPVTNLSVS VENLCTVIWT WNPPEGASSN CSLWYFSHFG DKQDKKIAPE TRRSIEVPLN ERICLQVGSQ CSTNESEKPS ILVEKCISPP EGDPESAVTE LQCIWHNLSY MKCSWLPGRN TSPDTNYTLY YWHRSLEKIH QCENIFREGQ YFGCSFDLTK VKDSSFEQHS VQIMVKDNAG KIKPSFNIVP LTSRVKPDPP HIKNLSFHND DLYVQWENPQ NFISRCLFYE VEVNNSQTET HNVFYVQEAK CENPEFERNV ENTSCFMVPG VLPDTLNTVR IRVKTNKLCY EDDKLWSNWS QEMSIGKKRN STHHHHHH |
| Endotoxin : |
< 1.0 eu per 1 microgram of protein (determined by lal |
| Purity : |
>90% by SDS - PAGE. |
| Storage : |
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
| Concentration : |
0.5mg/ml (determined by Bradford assay) |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
