Recombinant Human IL13RA1, His-tagged IL13RA1-48H

Recombinant Human IL13RA1, His-tagged

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Cat.No. : IL13RA1-48H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human IL13RA1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description : IL13RA1, also known as Interleukin-13 receptor subunit alpha-1, is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. It is essential for allergen-induced airway hyperactivity and mucus hypersecretion.
Source : Insect cell
Species : Human
Tag : His
Form : Liquid. In Phosphate buffer saline (pH 7.4)
Molecular Mass : 37.7kDa (328aa) 40-57kDa (SDS-PAGE under reducing conditions.)
AA Sequence : GGGGAAPTET QPPVTNLSVS VENLCTVIWT WNPPEGASSN CSLWYFSHFG DKQDKKIAPE TRRSIEVPLN ERICLQVGSQ CSTNESEKPS ILVEKCISPP EGDPESAVTE LQCIWHNLSY MKCSWLPGRN TSPDTNYTLY YWHRSLEKIH QCENIFREGQ YFGCSFDLTK VKDSSFEQHS VQIMVKDNAG KIKPSFNIVP LTSRVKPDPP HIKNLSFHND DLYVQWENPQ NFISRCLFYE VEVNNSQTET HNVFYVQEAK CENPEFERNV ENTSCFMVPG VLPDTLNTVR IRVKTNKLCY EDDKLWSNWS QEMSIGKKRN STHHHHHH
Endotoxin : < 1.0 eu per 1 microgram of protein (determined by lal
Purity : >90% by SDS - PAGE.
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5mg/ml (determined by Bradford assay)
Gene Name : IL13RA1 interleukin 13 receptor, alpha 1 [ Homo sapiens ]
Official Symbol : IL13RA1
Synonyms : IL13RA1; interleukin 13 receptor, alpha 1; interleukin-13 receptor subunit alpha-1; CD213a1; CD213a1 antigen; IL 13Ra; IL13 receptor alpha 1 chain; NR4; CT19; IL-13RA1; IL-13R-alpha-1; IL-13R subunit alpha-1; cancer/testis antigen 19; IL13 receptor alpha-1 chain; IL-13 receptor subunit alpha-1; bB128O4.2.1 (interleukin 13 receptor, alpha 1); CD213A1; IL-13Ra;
Gene ID : 3597
mRNA Refseq : NM_001560
Protein Refseq : NP_001551
MIM : 300119
UniProt ID : P78552
Chromosome Location : Xq24
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL-4 signaling Pathway, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine receptor activity; protein binding; receptor activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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