Recombinant Human IL23R protein, His-tagged
Cat.No. : | IL23R-589H |
Product Overview : | Recombinant Human IL23R (Gly24-Gly355) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Interleukin 23 receptor (IL-23R) is a type I cytokine receptor, and IL-23R pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. Also, IL-23R associates constitutively with Janus kinase 2 (JAK2), and binds to transcription activator STAT3 in a ligand-dependent manner. Furthermore, IL-23R mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. As for IL-23, it may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Gly24 |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 39.9 kDa. The protein migrates as 55-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Gly24-Gly355 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >90% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL23R |
Official Symbol : | IL23R |
Synonyms : | IL23R; interleukin 23 receptor; interleukin-23 receptor; IL 23R; IL-23 receptor |
Gene ID : | 149233 |
mRNA Refseq : | NM_144701 |
Protein Refseq : | NP_653302 |
MIM : | 607562 |
UniProt ID : | Q5VWK5 |
Products Types
◆ Recombinant Protein | ||
Il23r-1030R | Recombinant Rat Il23r Protein, His-tagged | +Inquiry |
Il23r-71M | Recombinant Mouse Il23r Protein, His (Fc)-Avi-tagged | +Inquiry |
Il23r-327M | Recombinant Mouse Il23r Protein, Fc-tagged | +Inquiry |
Il23r-8801R | Active Recombinant Rat Il23r protein(Met1-Asp367), hFc-tagged | +Inquiry |
IL23R-348M | Active Recombinant Mouse IL23R protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
IL23R-1234RCL | Recombinant Rat IL23R cell lysate | +Inquiry |
IL23R-1429CCL | Recombinant Cynomolgus IL23R cell lysate | +Inquiry |
IL23R-1213HCL | Recombinant Human IL23R cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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