Active Recombinant Cynomolgus IL23R protein, Fc-tagged
Cat.No. : | IL23R-0271C |
Product Overview : | Recombinant Cynomolgus IL23R protein(Gly24-Asp353), fused with Fc tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant. |
Bio-activity : | Immobilized Biotinylated Human IL-23A&IL-12B Heterodimer Protein, His,Avitag&Tag Free at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate can bind Cynomolgus IL-23 R, Fc Tag with a linear range of 0.1-3 ng/mL. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the C-terminusThe protein has a calculated MW of 64.5 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Proteinlength : | Gly24-Asp353 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Official Symbol : | IL23R |
Official Symbol : | IL23R |
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◆ Lysates | ||
IL23R-1429CCL | Recombinant Cynomolgus IL23R cell lysate | +Inquiry |
IL23R-1213HCL | Recombinant Human IL23R cell lysate | +Inquiry |
IL23R-1234RCL | Recombinant Rat IL23R cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionIL23R activation promotes Th17 cell differentiation.
IL23R has multiple alternative splicing variants.
IL23R undergoes phosphorylation that affects its stability.
The half-life of IL23R protein in activated T-cells is approximately 48 hours.
MicroRNAs like miR-20a regulate IL23R expression.
IL23R contributes to the release of pro-inflammatory cytokines like IL-17.
IL23R is implicated in autoimmune diseases like Crohn's.
IL23R expression is upregulated during bacterial infection.
IL23R forms heterodimers with IL-12Rβ1.
IL23R activates the JAK-STAT and NF-κB pathways.
Customer Reviews (3)
Write a reviewHigh specificity in ELISA. -
Effective in autoimmune models. -
Suitable for receptor binding studies. -
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