Active Recombinant Mouse IL23R protein, His-tagged

Cat.No. : IL23R-135M
Product Overview : Recombinant Mouse IL23R protein(Q8K4B4)(Gly24-Gly374), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from 0.22 μm filtered solution in PBS, pH7.4.
Bio-activity : IL-23 (mouse):FC (human) (rec.) captured on Protein A chip, can bind Recombinant Mouse IL-23R/His Protein with a KD constant of 1.55E-06 M, determined in a SPR assay.
Molecular Mass : The protein has a calculated MW of 41kDa.The reducing (R) heterodimer protein migrates as 60-100 kDa due to glycosylation
Protein Length : Gly24-Gly374
Endotoxin : <1EU/mg
Purity : SDS-PAGE>90%,SEC>95%
Storage : Store at -20°C.
Reconstitution : sterile H54O
Gene Name : Il23r interleukin 23 receptor [ Mus musculus ]
Official Symbol : IL23R
Synonyms : IL23R; interleukin 23 receptor; interleukin-23 receptor; IL-23 receptor; IL-23R;
Gene ID : 209590
mRNA Refseq : NM_144548
Protein Refseq : NP_653131

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does IL23R activation affect T-cell differentiation? 12/22/2022

IL23R activation promotes Th17 cell differentiation.

Does IL23R have alternative splicing variants? 02/20/2022

IL23R has multiple alternative splicing variants.

Does IL23R have any post-translational modifications that affect its stability? 08/23/2021

IL23R undergoes phosphorylation that affects its stability.

What is the half-life of IL23R protein in activated T-cells? 08/21/2020

The half-life of IL23R protein in activated T-cells is approximately 48 hours.

Are there any microRNAs that regulate IL23R expression? 06/16/2020

MicroRNAs like miR-20a regulate IL23R expression.

How does IL23R contribute to cytokine release? 02/15/2019

IL23R contributes to the release of pro-inflammatory cytokines like IL-17.

What role does IL23R play in autoimmune diseases? 08/22/2018

IL23R is implicated in autoimmune diseases like Crohn's.

How does IL23R expression change during infection? 10/12/2017

IL23R expression is upregulated during bacterial infection.

Does IL23R form homodimers or heterodimers? 08/15/2016

IL23R forms heterodimers with IL-12Rβ1.

What intracellular pathways are activated by IL23R? 08/06/2016

IL23R activates the JAK-STAT and NF-κB pathways.

Customer Reviews (3)

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Reviews
10/21/2020

    High specificity in ELISA.

    04/28/2016

      Effective in autoimmune models.

      03/30/2016

        Suitable for receptor binding studies.

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