Active Recombinant Mouse IL23R protein, His-tagged
| Cat.No. : | IL23R-135M |
| Product Overview : | Recombinant Mouse IL23R protein(Q8K4B4)(Gly24-Gly374), fused with His tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
| Source : | HEK293 |
| Species : | Mouse |
| Tag : | His |
| Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. |
| Bio-activity : | IL-23 (mouse):FC (human) (rec.) captured on Protein A chip, can bind Recombinant Mouse IL-23R/His Protein with a KD constant of 1.55E-06 M, determined in a SPR assay. |
| Molecular Mass : | The protein has a calculated MW of 41kDa.The reducing (R) heterodimer protein migrates as 60-100 kDa due to glycosylation |
| Protein Length : | Gly24-Gly374 |
| Endotoxin : | <1EU/mg |
| Purity : | SDS-PAGE>90%，SEC>95% |
| Storage : | Store at -20°C. |
| Reconstitution : | sterile H54O |
| Gene Name : | Il23r interleukin 23 receptor [ Mus musculus ] |
| Official Symbol : | IL23R |
| Synonyms : | IL23R; interleukin 23 receptor; interleukin-23 receptor; IL-23 receptor; IL-23R; |
| Gene ID : | 209590 |
| mRNA Refseq : | NM_144548 |
| Protein Refseq : | NP_653131 |
Products Types
| ◆ Recombinant Protein | ||
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| ◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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- Reviews
Q&As (10)
Ask a questionIL23R activation promotes Th17 cell differentiation.
IL23R has multiple alternative splicing variants.
IL23R undergoes phosphorylation that affects its stability.
The half-life of IL23R protein in activated T-cells is approximately 48 hours.
MicroRNAs like miR-20a regulate IL23R expression.
IL23R contributes to the release of pro-inflammatory cytokines like IL-17.
IL23R is implicated in autoimmune diseases like Crohn's.
IL23R expression is upregulated during bacterial infection.
IL23R forms heterodimers with IL-12Rβ1.
IL23R activates the JAK-STAT and NF-κB pathways.
Customer Reviews (3)
Write a reviewHigh specificity in ELISA. -
Effective in autoimmune models. -
Suitable for receptor binding studies. -
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