Recombinant Human IMPA2 Protein, GST-tagged
Cat.No. : | IMPA2-5143H |
Product Overview : | Human IMPA2 full-length ORF ( NP_055029.1, 1 a.a. - 288 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This locus encodes an inositol monophosphatase. The encoded protein catalyzes the dephosphoylration of inositol monophosphate and plays an important role in phosphatidylinositol signaling. This locus may be associated with susceptibility to bipolar disorder. [provided by RefSeq, Jan 2011] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 57.7 kDa |
AA Sequence : | MKPSGEDQAALAAGPWEECFQAAVQ LALRAGQIIRKALTEEKRVSTKTSA ADLVTETDHLVEDLIISELRERFPS HRFIAEEAAASGAKCVLTHSPTWII DPIDGTCNFVHRFPTVAVSIGFAVR QELEFGVIYHCTEERLYTGRRGRGA FCNGQRLRVSGETDLSKALVLTEIG PKRDPATLKLFLSNMERLLHAKAHG VRVIGSSTLALCHLASGAADAYYQF GLHCWDLAAATVIIREAGGIVIDTS GGPLDLMACRVVAASTREMAMLIAQ ALQTINYGRDDEK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 [ Homo sapiens ] |
Official Symbol : | IMPA2 |
Synonyms : | IMPA2; inositol(myo)-1(or 4)-monophosphatase 2; inositol monophosphatase 2; IMP 2; IMPase 2; inosine monophosphatase 2; myo-inositol monophosphatase A2; inositol monophosphatase 2 variant 1; inositol monophosphatase 2 variant 2; |
Gene ID : | 3613 |
mRNA Refseq : | NM_014214 |
Protein Refseq : | NP_055029 |
MIM : | 605922 |
UniProt ID : | O14732 |
Products Types
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IMPA2-2085R | Recombinant Rhesus Macaque IMPA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IMPA2-2713R | Recombinant Rat IMPA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IMPA2-29492TH | Recombinant Human IMPA2, His-tagged | +Inquiry |
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◆ Lysates | ||
IMPA2-5213HCL | Recombinant Human IMPA2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionIMPA2, short for Inositol monophosphatase 2, is the gene encoding the related enzyme. It is widely expressed in the human body, but the specific expression pattern may vary among tissues and organs.
The association between IMPA2 and neurodegenerative diseases may be related to its role in the intracellular inositol metabolic pathway. More research is needed to advance our understanding of this association.
No drugs have been identified that directly regulate IMPA2 activity. However, there are other ways to regulate the intracellular inositol metabolic pathway to affect the function of IMPA2.
Several studies have suggested that IMPA2 may be associated with psychiatric disorders such as bipolar disorder and schizophrenia, as well as neurological disorders such as degenerative neurological disorders and neurodysplasia.
It is involved in the intracellular inositol metabolic pathway, which is one of the key biological processes for intracellular signaling and neurotransmitter synthesis.
IMPA2 may be involved in physiological mechanisms related to neurotransmitter synthesis and neurotransmission in psychiatric disorders. The specific mechanism and regulation mode need to be further studied.
Customer Reviews (3)
Write a reviewPurity and biological activity are very good, which makes its products have extremely high reliability.
After using this recombinant protein, my experiment repeatability is very good, which is convenient for subsequent data analysis and experimental operation.
The background in the Western blot was very clean and showed good antibody specificity.
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