Recombinant Human INCENP, His-tagged
Cat.No. : | INCENP-7037H |
Product Overview : | Recombinant human INCENP (783-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. This product can be used for Aurora B and Aurora C activation in vitro. |
- Specification
- Gene Information
- Related Products
Description : | INCENP or inner centromere protein antigens 135/155kDa is a constitutively binding centromere proteins and passenger, or transiently interacting, proteins. Theoverexpression of a truncation mutant of chicken INCENP and a chimeric CENPB:INCENP protein in mammalian cell culture disrupted both prometaphase chromosome alignment and completion of cytokinesis. INCENP forms a complex with the evolutionarily conserved family of Aurora B kinases which helps coordinate chromosome segregation, spindle behavior, and cytokinesis during mitosis. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | His |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Molecular Mass : | ~19 kDa |
Protein length : | 783 aa-end |
Purity : | >90% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | INCENP inner centromere protein antigens 135/155kDa [ Homo sapiens ] |
Official Symbol : | INCENP |
Synonyms : | INCENP; inner centromere protein antigens 135/155kDa; inner centromere protein antigens (135kD, 155kD); inner centromere protein; FLJ31633; chromosomal passenger protein; inner centromere protein INCENP; binds and activates aurora-B and -C in vivo and in vitro; MGC111393; |
Gene ID : | 3619 |
mRNA Refseq : | NM_001040694 |
Protein Refseq : | NP_001035784 |
MIM : | 604411 |
UniProt ID : | Q9NQS7 |
Chromosome Location : | 11q12.3 |
Pathway : | Aurora B signaling, organism-specific biosystem; Aurora C signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem; |
Function : | protein binding; |
Products Types
◆ Recombinant Protein | ||
INCENP-4541M | Recombinant Mouse INCENP Protein, His (Fc)-Avi-tagged | +Inquiry |
INCENP-8205M | Recombinant Mouse INCENP Protein | +Inquiry |
INCENP-6882C | Recombinant Chicken INCENP | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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