"INS" Related Products

Recombinant Human INS Protein, GST-tagged

Cat.No.: INS-5100H
Product Overview: Human INS full-length ORF ( AAH05255.1, 1 a.a. - 110 a.a.) recombinant protein with GST-tag at N-terminal.
Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. [provided by RefSeq
Source: Wheat Germ
Species: Human
Tag : GST
Molecular Mass: 38.4 kDa
AA Sequence: MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCGERGFFYTPKTRREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQLENYCN
Applications: Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes: Best use within three months from the date of receipt of this protein.
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name: INS insulin [ Homo sapiens ]
Official Symbol: INS
Synonyms: INS; insulin; proinsulin; ILPR; IRDN; IDDM2; MODY10;
Gene ID: 3630
mRNA Refseq: NM_000207
Protein Refseq: NP_000198
UniProt ID: P01308

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