Recombinant Human insulin-like growth factor binding protein 6, His-tagged

• Cat.No.: IGFBP6-82H
• Product Overview: Recombinant Human IGFBP6 produced inE.Coliis a single, non-glycosylated, polypeptide chain containing amino acids 148-240 and having a molecular mass of 20 kDa including 4kDa His-tagged. IGFBP6 is purified by proprietary chromatographic techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 148-240 a.a.
• Description: IGFBP6 plays a role in lipoprotein assembly and dietary cholesterol absorption. in addition to its acyltransferase activity, it may act as a ligase. may provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
• Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
• Purity: Greater than 80.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
• Formulation: IBP-6 was lyophilized from a concentrated (1mg/ml) solution containing 1XPBS, 0.1% SDS and 1 mM DTT.
• Solubility: It is recommended to reconstitute the lyophilized Insulin-Like Growth Factor Binding Protein-6 in sterile 18 MΩ-cm H₂O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
• Stability: Lyophilized IBP5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IGFBP 5 should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1%HSA or BSA). Please prevent freeze-thaw cycles.
• Applications: 1. Positive control for Western Blot; 2. Antibody production; 3. Protein Assay

Gene Information

• Gene Name: IGFBP6 insulin-like growth factor binding protein 6 [ Homo sapiens ]
• Synonyms: IGFBP6; insulin-like growth factor binding protein 6; IBP6; IGF binding protein 6; Insulin-like growth factor-binding protein 6; IGF-binding protein 6; IGFBP-6; IBP-6
• Gene ID: 3489
• mRNA Refseq: NM_002178
• Protein Refseq: NP_002169
• MIM: 146735
• UniProt ID: P24592
• Chromosome Location: 12q13
• Pathway: Diabetes pathways
• Function: insulin-like growth factor I binding; insulin-like growth factor II binding