Recombinant Human Interferon, Alpha 1

• Cat.No.: IFNA1-16H
• Product Overview: Recombinant human Interferon- α was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer(167 aa, 19.5 kDa).

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Interferon- α is cytokines that are widely known to induce potent anti-viral activity. Interferon -α exerts a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases.
• Formulation: Liquid. In phosphate-buffered Saline(pH 7.4).
• Molecular Weight: 19.5kDa (167aa).
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Amino acid Sequence: MCDLPETHSL DNRRTLMLLA QMSRISPSSC LMDRHDFGFP QEEFDGNQFQ KAPAISVLHE LIQQIFNLFT TKDSSAAWDE DLLDKFCTEL YQQLNDLEAC VMQEERVGET PLMNVDSILA VKKYFRRITL YLTEKKYSPC AWEVVRAEIM RSLSLSTNLQ ERLRRKE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: IFNA1 interferon, alpha 1 [ Homo sapiens ]
• Synonyms: IFL; IFN; IFN-ALPHA; IFNA13; IFNA@; MGC138505; MGC138507; OTTHUMP00000045110; IFN-alpha 1b; Interferon alpha-D; LeIF D; interferon alpha 1b; interferon, alpha 1; IFNA1.
• Gene ID: 3439
• mRNA Refseq: NM_024013
• Protein Refseq: NP_076918
• MIM: 147660
• UniProt ID: P01562
• Chromosome Location: 9p22
• Pathway: Antigen processing and presentation; Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Regulation of autophagy; Toll-like receptor signaling pathway.