Recombinant Human INTS5 Protein, GST-tagged

• Cat.No.: INTS5-5086H
• Product Overview: Human INTS5 full-length ORF ( NP_085131.1, 1 a.a. - 1019 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 134.4 kDa
• AA Sequence: MSALCDPPGAPGPPGPAPATHGPAP LSAQELSQEIKAFLTGVDPILGHQL SAREHARCGLLLLRSLPPARAAVLD HLRGVFDESVRAHLAALDETPVAGP PHLRPPPPSHVPAGGPGLEDVVQEV QQVLSEFIRANPKAWAPVISAWSID LMGQLSSTYSGQHQRVPHATGALNE LLQLWMGCRATRTLMDIYVQCLSAL IGSCPDACVDALLDTSVQHSPHFDW VVAHIGSSFPGTIISRVLSCGLKDF CVHGGAGGGAGSSGGSSSQTPSTDP FPGSPAIPAEKRVPKIASVVGILGH LASRHGDSIRRELLRMFHDSLAGGS GGRSGDPSLQATVPFLLQLAVMSPA LLGTVSGELVDCLKPPAVLSQLQQH LQGFPREELDNMLNLAVHLVSQASG AGAYRLLQFLVDTAMPASVITTQGL AVPDTVREACDRLIQLLLLHLQKLV HHRGGSPGEGVLGPPPPPRLVPFLD ALKNHVGELCGETLRLERKRFLWQH QLLGLLSVYTRPSCGPEALGHLLSR ARSPEELSLATQLYAGLVVSLSGLL PLAFRSCLARVHAGTLQPPFTARFL RNLALLVGWEQQGGEGPAALGAHFG ESASAHLSDLAPLLLHPEEEVAEAA ASLLAICPFPSEALSPSQLLGLVRA GVHRFFASLRLHGPPGVASACQLLT RLSQTSPAGLKAVLQLLVEGALHRG NTELFGGQVDGDNETLSVVSASLAS ASLLDTNRRHTAAVPGPGGIWSVFH AGVIGRGLKPPKFVQSRNQQEVIYN TQSLLSLLVHCCSAPGGTECGECWG APILSPEAAKAVAVTLVESVCPDAA GAELAWPPEEHARATVERDLRIGRR FREQPLLFELLKLVAAAPPALCYCS VLLRGLLAALLGHWEASRHPDTTHS PWHLEASCTLVAVMAEGSLLPPALG NMHEVFSQLAPFEVRLLLLSVWGFL REHGPLPQKFIFQSERGRFIRDFSR EGGGEGGPHLAVLHSVLHRNIDRLG LFSGRFQAPSPSTLLRQGT
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INTS5 integrator complex subunit 5 [ Homo sapiens ]
• Official Symbol: INTS5
• Synonyms: INTS5; integrator complex subunit 5; KIAA1698; INT5
• Gene ID: 80789
• mRNA Refseq: NM_030628
• Protein Refseq: NP_085131
• MIM: 611349
• UniProt ID: Q6P9B9