Recombinant Human ITIH2 protein, His & T7-tagged

• Cat.No.: ITIH2-1569H
• Product Overview: Recombinant Human ITIH2 aa. (Gly452~Asp702 (Accession # P19823)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]).
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.6kDa
• Protein length: Gly452~Asp702 (Accession # P19823)
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 5.9

Gene Information

• Gene Name: ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 [ Homo sapiens (human) ]
• Official Symbol: ITIH2
• Synonyms: ITIH2; inter-alpha-trypsin inhibitor heavy chain 2; H2P; SHAP; inter-alpha-trypsin inhibitor heavy chain H2; ITI heavy chain H2; ITI-HC2; inter-alpha (globulin) inhibitor H2; inter-alpha (globulin) inhibitor, H2 polypeptide; inter-alpha-inhibitor heavy chain 2; inter-alpha-trypsin inhibitor complex component II; serum-derived hyaluronan-associated protein
• Gene ID: 3698
• mRNA Refseq: NM_002216.2
• Protein Refseq: NP_002207.2
• UniProt ID: P19823