Recombinant Human ITK Protein, GST-tagged

• Cat.No.: ITK-4960H
• Product Overview: Human ITK full-length ORF ( AAI09078.1, 1 a.a. - 620 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 98.2 kDa
• AA Sequence: MNNFILLEEQLIKKSQQKRRTSPSN FKVRFFVLTKASLAYFEDRHGKKRT LKGSIELSRIKCVEIVKSDISIPCH YKYPFQVVHDNYLLYVFAPDRESRQ RWVLALKEETRNNNSLVPKYHPNFW MDGKWRCCSQLEKLATGCAQYDPTK NASKKPLPPTPEDNRRPLWEPEETV VIALYDYQTNDPQELALRRNEEYCL LDSSEIHWWRVQDRNGHEGYVPSSY LVEKSPNNLETYEWYNKSISRDKAE KLLLDTGKEGAFMVRDSRTAGTYTV SVFTKAVVSENNPCIKHYHIKETND NPKRYYVAEKYVFDSIPLLINYHQH NGGGLVTRLRYPVCFGRQKAPVTAG LRYGKWVIDPSELTFVQEIGSGQFG LVHLGYWLNKDKVAIKTIREGAMSE EDFIEEAEVMMKLSHPKLVQLYGVC LEQAPICLVFEFMEHGCLSDYLRTQ RGLFAAETLLGMCLDVCEGMAYLEE ACVIHRDLAARNCLVGENQVIKVSD FGMTRFVLDDQYTSSTGTKFPVKWA SPEVFSFSRYSSKSDVWSFGVLMWE VFSEGKIPYENRSNSEVVEDISTGF RLYKPRLASTHVYQIMNHCWKERPE DRPAFSRLLRQLAEIAESGL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ITK IL2-inducible T-cell kinase [ Homo sapiens ]
• Official Symbol: ITK
• Synonyms: ITK; IL2-inducible T-cell kinase; tyrosine-protein kinase ITK/TSK; EMT; LYK; PSCTK2; kinase EMT; T-cell-specific kinase; tyrosine-protein kinase LYK; IL-2-inducible T cell kinase; IL-2-inducible T-cell kinase; homolog of mouse T-cell itk/tsk; interleukin-2-inducible T cell kinase; interleukin-2-inducible T-cell kinase; MGC126257; MGC126258
• Gene ID: 3702
• mRNA Refseq: NM_005546
• Protein Refseq: NP_005537
• MIM: 186973
• UniProt ID: Q08881