Recombinant Human JAZF zinc finger 1, His-tagged

• Cat.No.: JAZF1-557H
• Product Overview: JAZF1, 1-243aa, Human His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-243 a.a.
• Description: JAZF1 is a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. Recombinant human JAZF1 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
• Molecular Mass: 29.5kDa (266aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTGIAAA SFFSNTCRFG GCGLHFPTLA DLIEHIEDNH IDTDPRVLEK QELQQPTYVA LSYINRFMTD AARREQESLK KKIQPKLSLT LSSSVSRGNV STPPRHSSGS LTPPVTPPIT PSSSFRSSTP TGSEYDEEEV DYEESDSDES WTTESAISSE AILSSMCMNG GEEKPFACPV PGCKKRYKNV NGIKYHAKNG HRTQIRVRKP FKCRCGKSYK TAQGLRHHTI NFHPPVSAEI IRKMQQ
• Purity: >85% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: JAZF1 JAZF zinc finger 1 [ Homo sapiens ]
• Official Symbol: JAZF1
• Synonyms: JAZF1; JAZF zinc finger 1; juxtaposed with another zinc finger protein 1; DKFZp761K2222; TIP27; ZNF802; zinc finger protein 802; TAK1-interacting protein 27; juxtaposed with another zinc finger gene 1
• Gene ID: 221895
• mRNA Refseq: NM_175061
• Protein Refseq: NP_778231
• MIM: 606246
• UniProt ID: Q86VZ6
• Chromosome Location: 7p15.2-p15.1
• Function: metal ion binding; nucleic acid binding; transcription corepressor activity; zinc ion binding