| Description : |
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
72.3 kDa |
| AA Sequence : |
MATPVVTKTAWKLQEIVAHASNVSS LVLGKASGRLLATGGDDCRVNLWSI NKPNCIMSLTGHTSPVESVRLNTPE ELIVAGSQSGSIRVWDLEAAKILRT LMGHKANICSLDFHPYGEFVASGSQ DTNIKLWDIRRKGCVFRYRGHSQAV RCLRFSPDGKWLASAADDHTVKLWD LTAGKMMSEFPGHTGPVNVVEFHPN EYLLASGSSDRTIRFWDLEKFQVVS CIEGEPGPVRSVLFNPDGCCLYSGC QDSLRVYGWEPERCFDVVLVNWGKV ADLAICNDQLIGVAFSQSNVSSYVV DLTRVTRTGTVARDPVQDHRPLAQP LPNPSAPLRRIYERPSTTCSKPQRV KQNSESERRSPSSEDDRDERESRAE IQNAEDYNEIFQPKNSISRTPPRRS EPFPAPPEDDAATAKEAAKPSPAMD VQFPVPNLEVLPRPPVVASTPAPKA EPAIIPATRNEPIGLKASDFLPAVK IPQQAELVDEDAMSQIRKGHDTMCV VLTSRHKNLDTVRAVWTMGDIKTSV DSAVAINDLSVVVDLLNIVNQKASL WKLDLCTTVLPQIEKLLQSKYESYV QTGCTSLKLILQRFLPLITDMLAAP PSVGVDISREERLHKCRLCYKQLKS ISGLVKSKSGLSGRHGSTFRELHLL MASLDSGPTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
