Recombinant Human KLC2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: KLC2-765H
• Product Overview: KLC2 MS Standard C13 and N15-labeled recombinant protein (NP_001128247) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 68.9 kDa
• AA Sequence: MAMMVFPREEKLSQDEIVLGTKAVI QGLETLRGEHRALLAPLVAPEAGEA EPGSQERCILLRRSLEAIELGLGEA QVILALSSHLGAVESEKQKLRAQVR RLVQENQWLREELAGTQQKLQRSEQ AVAQLEEEKQHLLFMSQIRKLDEDA SPNEEKGDVPKDTLDDLFPNEDEQS PAPSPGGGDVSGQHGGYEIPARLRT LHNLVIQYASQGRYEVAVPLCKQAL EDLEKTSGHDHPDVATMLNILALVY RDQNKYKEAAHLLNDALAIREKTLG KDHPAVAATLNNLAVLYGKRGKYKE AEPLCKRALEIREKVLGKFHPDVAK QLSNLALLCQNQGKAEEVEYYYRRA LEIYATRLGPDDPNVAKTKNNLASC YLKQGKYQDAETLYKEILTRAHEKE FGSVNGDNKPIWMHAEEREESKDKR RDSAPYGEYGSWYKACKVDSPTVNT TLRSLGALYRRQGKLEAAHTLEDCA SRNRKQGLDPASQTKVVELLKDGSG RRGDRRSSRDMAGGAGPRSESDLED VGPTAEWNGDGSGSLRRSGSFGKLR DALRRSSEMLVKKLQGGTPQEPPNP RMKRASSLNFLNKSVEEPTQPGGTG LSDSRTLSSSSMDLSRRSSLVGTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KLC2 kinesin light chain 2 [ Homo sapiens (human) ]
• Official Symbol: KLC2
• Synonyms: KLC2; kinesin light chain 2; FLJ12387; KLC 2
• Gene ID: 64837
• mRNA Refseq: NM_001134775
• Protein Refseq: NP_001128247
• MIM: 611729
• UniProt ID: Q9H0B6