Recombinant Human KLF3, His-tagged

• Cat.No.: KLF3-15893H
• Product Overview: Recombinant human KLF3 protein, fused to His tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-345aa
• Description: Krueppel-like factor3, also known as KLF3, is a member of the Sp1-like/KLF family. Kruppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. KLF3 is Kruppel-like zinc finger containing transcription factors. KLF3 may play a role in hematopoiesis.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 41.2 kDa (368aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMLMFDPV PVKQEAMDPV SVSYPSNYME SMKPNKYGVI YSTPLPEKFF QTPEGLSHGI QMEPVDLTVN KRSSPPSAGN SPSSLKFPSS HRRASPGLSM PSSSPPIKKY SPPSPGVQPF GVPLSMPPVM AAALSRHGIR SPGILPVIQP VVVQPVPFMY TSHLQQPLMV SLSEEMENSS SSMQVPVIES YEKPISQKKI KIEPGIEPQR TDYYPEEMSP PLMNSVSPPQ ALLQENHPSV IVQPGKRPLP VESPDTQRKR RIHRCDYDGC NKVYTKSSHL KAHRRTHTGE KPYKCTWEGC TWKFARSDEL TRHFRKHTGI KPFQCPDCDR SFSRSDHLAL HRKRHMLV
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: KLF3 Kruppel-like factor 3 (basic) [ Homo sapiens ]
• Official Symbol: KLF3
• Synonyms: KLF3; Kruppel-like factor 3 (basic); Krueppel-like factor 3; basic Kruppel like factor; BKLF; TEF-2; transcript ch138; basic Kruppel-like factor; basic kruppel like factor; basic krueppel-like factor; CACCC-box-binding protein BKLF; MGC48279
• Gene ID: 51274
• mRNA Refseq: NM_016531
• Protein Refseq: NP_057615
• MIM: 609392
• UniProt ID: P57682
• Chromosome Location: 4p16.1-p15.2
• Pathway: Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem
• Function: DNA binding; metal ion binding; sequence-specific DNA binding transcription factor activity; zinc ion binding