Active Recombinant Human KLRK1 protein, hFc-tagged

• Cat.No.: KLRK1-350H
• Product Overview: Active Recombinant Human KLRK1 protein(NP_031386.2)(Phe78-Val216) was expressed in CHO with the Fc region of human IgG1 at the N-terminus.

Specification

• Species: Human
• Source: CHO
• Tag: Fc
• Protein Length: 78-216 aa
• Form: Lyophilized from sterile PBS, pH 7.4.
• Bio-activity: Immobilized human ULBP1-His at 10 μg/ml (100 μl/well) can bind human S4-Fc3L3-NKG2D, The EC50 of human S4-Fc3L3-NKG2D is 0.39-0.91 μg/ml.
• Molecular Mass: The recombinant human NKG2D/Fc comprises 418 amino acids and has a predicted molecular mass of 46.5 kDa. The apparent molecular mass of the protein is approximately 50-64 and 37 kDa in SDS-PAGE under reducing conditions.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: (81.4+13.9) % as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: KLRK1 killer cell lectin-like receptor subfamily K, member 1 [ Homo sapiens ]
• Official Symbol: KLRK1
• Synonyms: KLRK1; killer cell lectin-like receptor subfamily K, member 1; D12S2489E, DNA segment on chromosome 12 (unique) 2489 expressed sequence; NKG2-D type II integral membrane protein; CD314; KLR; NKG2 D; NKG2D; NK cell receptor D; NKG2-D-activating NK receptor; NKG2-D; D12S2489E; FLJ17759; FLJ75772
• Gene ID: 22914
• mRNA Refseq: NM_007360
• Protein Refseq: NP_031386
• MIM: 611817
• UniProt ID: P26718