Recombinant Human KMO Protein (1-486 aa), His-SUMO-tagged
Cat.No. : | KMO-607H |
Product Overview : | Recombinant Human KMO Protein (1-486 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Metabolism. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. |
Source : | E. coli |
Species : | Human |
Tag : | His-SUMO |
Form : | Tris-based buffer, 50% glycerol |
Molecular Mass : | 71.8 kDa |
Protein length : | 1-486 aa |
AA Sequence : | MDSSVIQRKKVAVIGGGLVGSLQAC FLAKRNFQIDVYEAREDTRVATFTR GRSINLALSHRGRQALKAVGLEDQI VSQGIPMRARMIHSLSGKKSAIPYG TKSQYILSVSRENLNKDLLTAAEKY PNVKMHFNHRLLKCNPEEGMITVLG SDKVPKDVTCDLIVGCDGAYSTVRS HLMKKPRFDYSQQYIPHGYMELTIP PKNGDYAMEPNYLHIWPRNTFMMIA LPNMNKSFTCTLFMPFEEFEKLLTS NDVVDFFQKYFPDAIPLIGEKLLVQ DFFLLPAQPMISVKCSSFHFKSHCV LLGDAAHAIVPFFGQGMNAGFEDCL VFDELMDKFSNDLSLCLPVFSRLRI PDDHAISDLSMYNYIEMRAHVNSSW FIFQKNMERFLHAIMPSTFIPLYTM VTFSRIRYHEAVQRWHWQKKVINKG LFFLGSLIAISSTYLLIHYMSPRSF LRLRRPWNWIAHFRNTTCFPAKAVD SLEQISNLISR |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with concentration instruction is sent along with the products. |
Gene Name : | KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) [ Homo sapiens ] |
Official Symbol : | KMO |
Synonyms : | KMO; dJ317G22.1; |
Gene ID : | 8564 |
mRNA Refseq : | NM_003679 |
Protein Refseq : | NP_003670 |
MIM : | 603538 |
UniProt ID : | O15229 |
Products Types
◆ Recombinant Protein | ||
KMO-4904H | Recombinant Human KMO Protein, GST-tagged | +Inquiry |
KMO-4890M | Recombinant Mouse KMO Protein, His (Fc)-Avi-tagged | +Inquiry |
KMO-1259H | Recombinant Human KMO Protein, His (Fc)-Avi-tagged | +Inquiry |
KMO-2957R | Recombinant Rat KMO Protein, His (Fc)-Avi-tagged | +Inquiry |
KMO-07H | Active Recombinant Human KMO Protein, N-6×His tagged | +Inquiry |
◆ Lysates | ||
KMO-951HCL | Recombinant Human KMO cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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