Recombinant Human KRT14 Protein (1-472 aa), His-tagged

• Cat.No.: KRT14-1437H
• Product Overview: Recombinant Human KRT14 Protein (1-472 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length.

Specification

• Description: The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 53.6 kDa
• Protein length: 1-472 aa
• AA Sequence: MTTCSRQFTSSSSMKGSCGIGGGIG GGSSRISSVLAGGSCRAPSTYGGGL SVSSSRFSSGGACGLGGGYGGGFSS SSSSFGSGFGGGYGGGLGAGLGGGF GGGFAGGDGLLVGSEKVTMQNLNDR LASYLDKVRALEEANADLEVKIRDW YQRQRPAEIKDYSPYFKTIEDLRNK ILTATVDNANVLLQIDNARLAADDF RTKYETELNLRMSVEADINGLRRVL DELTLARADLEMQIESLKEELAYLK KNHEEEMNALRGQVGGDVNVEMDAA PGVDLSRILNEMRDQYEKMAEKNRK DAEEWFFTKTEELNREVATNSELVQ SGKSEISELRRTMQNLEIELQSQLS MKASLENSLEETKGRYCMQLAQIQE MIGSVEEQLAQLRCEMEQQNQEYKI LLDVKTRLEQEIATYRRLLEGEDAH LSSSQFSSGSQSSRDVTSSSRQIRT KVMDVHDGKVVSTHEQVLRTKN
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: KRT14 keratin 14 [ Homo sapiens ]
• Official Symbol: KRT14
• Synonyms: KRT14; Koebner; CK-14; keratin-14; cytokeratin 14; K14; NFJ; CK14; EBS3; EBS4
• Gene ID: 3861
• mRNA Refseq: NM_000526
• Protein Refseq: NP_000517
• MIM: 148066
• UniProt ID: P02533