Recombinant Human KYNU Protein, GST-tagged

• Cat.No.: KYNU-4785H
• Product Overview: Human KYNU full-length ORF ( NP_001028170.1, 1 a.a. - 307 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Kynureninase is a pyridoxal-5-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 61 kDa
• AA Sequence: MEPSSLELPADTVQRIAAELKCHPT DERVALHLDEEDKLRHFRECFYIPK IQDLPPVDLSLVNKDENAIYFLGNS LGLQPKMVKTYLEEELDKWAKIAAY GHEVGKRPWITGDESIVGLMKDIVG ANEKEIALMNALTVNLHLLMLSFFK PTPKRYKILLEAKAFPSDHYAIESQ LQLHGLNIEESMRMIKPREGEETLR IEDILEVIEKEGDSIAVILFSGVHF YTGQHFNIPAITKAGQAKGCYVGFD LAHAVGNVELYLHDWGVDFACWCSY KYLNAGAGGIAGAFIHEKHAHTIKP ARSEFFN
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KYNU kynureninase [ Homo sapiens ]
• Official Symbol: KYNU
• Synonyms: KYNU; kynureninase; kynureninase (L kynurenine hydrolase); L kynurenine hydrolase; kynureninase (L-kynurenine hydrolase)
• Gene ID: 8942
• mRNA Refseq: NM_001032998
• Protein Refseq: NP_001028170
• MIM: 605197
• UniProt ID: Q16719