Recombinant Human LAMP1 Protein, C-His-tagged

• Cat.No.: LAMP1-093H
• Product Overview: Recombinant Human LAMP1 Protein with C-His tag was expressed in E. coli.

Specification

• Description: Lysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and are heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplasm and contains a tyrosine sorting motif that targets LAMP to lysosomal membranes. LAMP1 and LAMP2 are 37% homologous in their protein sequences. Both LAMP1 and LAMP2 are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking.
• Source: E. coli
• Species: Human
• Tag: C-His
• Molecular Mass: ~39 kDa
• AA Sequence: AMFMVKNGNGTACIMANFSAAFSVN YDTKSGPKNMTFDLPSDATVVLNRS SCGKENTSDPSLVIAFGRGHTLTLN FTRNATRYSVQLMSFVYNLSDTHLF PNASSKEIKTVESITDIRADIDKKY RCVSGTQVHMNNVTVTLHDATIQAY LSNSSFSRGETRCEQDRPSPTTAPP APPSPSPSPVPKSPSVDKYNVSGTN GTCLLASMGLQLNLTYERKDNTTVT RLLNINPNKTSASGSCGAHLVTLEL HSEGTTVLLFQFGMNASSSRFFLQG IQLNTILPDARDPAFKAANGSLRAL QATVGNSYKCNAEEHVRVTKAFSVN IFKVWVQAFKVEGGQFGSVEECLLD ENSM
• Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
• Notes: For research use only, not for use in diagnostic procedure.
• Storage: Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
• Concentration: ≥0.5 mg/mL
• Storage Buffer: PBS, 4M Urea, pH7.4

Gene Information

• Gene Name: LAMP1 lysosomal-associated membrane protein 1 [ Homo sapiens (human) ]
• Official Symbol: LAMP1
• Synonyms: LAMP1; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; CD107a; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1; LAMPA; LGP120
• Gene ID: 3916
• mRNA Refseq: NM_005561
• Protein Refseq: NP_005552
• MIM: 153330
• UniProt ID: P11279