Recombinant Human LARP6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: LARP6-2897H
• Product Overview: LARP6 MS Standard C13 and N15-labeled recombinant protein (NP_932062) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 9.6 kDa
• AA Sequence: MAQSGGEARPGPKTAVQIRVAIQEA EDVDELEDEEEGAETRGAGDPARYL SPGWGSASEEEPSRGHRNRSSVNSR TMLASFIVSSAPSTAPSTTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: LARP6 La ribonucleoprotein 6, translational regulator [ Homo sapiens (human) ]
• Official Symbol: LARP6
• Synonyms: LARP6; La ribonucleoprotein domain family, member 6; la-related protein 6; acheron; FLJ11196; death-associated LA motif protein; ACHN
• Gene ID: 55323
• mRNA Refseq: NM_197958
• Protein Refseq: NP_932062
• MIM: 611300
• UniProt ID: Q9BRS8