Recombinant Human LGR5 Protein, Fc-tagged

• Cat.No.: LGR5-641H
• Product Overview: Recombinant Human LGR5(His447-Arg561) fused with Fc tag at C-terminal was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 447-561 a.a.
• Description: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
• Form: DPBS, 10% glycerol
• Molecular Mass: 38 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: LGR5 leucine-rich repeat containing G protein-coupled receptor 5 [ Homo sapiens ]
• Official Symbol: LGR5
• Synonyms: LGR5; leucine-rich repeat containing G protein-coupled receptor 5; G protein coupled receptor 49 , GPR49, GPR67, leucine rich repeat containing G protein coupled receptor 5; leucine-rich repeat-containing G-protein coupled receptor 5; FEX; HG38; G-protein coupled receptor 49; G-protein coupled receptor 67; G-protein coupled receptor HG38; orphan G protein-coupled receptor HG38; leucine-rich repeat-containing G protein-coupled receptor 5; GPR49; GPR67; GRP49; MGC117008
• Gene ID: 8549
• mRNA Refseq: NM_003667
• Protein Refseq: NP_003658
• MIM: 606667
• UniProt ID: O75473