Recombinant Human LOX Protein, His-tagged

• Cat.No.: LOX-1092H
• Product Overview: Recombinant Human LOX Protein (Asp169-Tyr417) with His tag was expressed in 293F.

Specification

• Description: This gene encodes a member of the lysyl oxidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a regulatory propeptide and the mature enzyme. The copper-dependent amine oxidase activity of this enzyme functions in the crosslinking of collagens and elastin, while the propeptide may play a role in tumor suppression. In addition, defects in this gene have been linked with predisposition to thoracic aortic aneurysms and dissections.
• Source: HEK293F
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 30.6 kDa; Accurate Molecular Mass: 33 kDa
• Protein length: Asp169-Tyr417
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: LOX lysyl oxidase [ Homo sapiens (human) ]
• Official Symbol: LOX
• Synonyms: LOX; lysyl oxidase; protein-lysine 6-oxidase; MGC105112
• Gene ID: 4015
• mRNA Refseq: NM_001178102
• Protein Refseq: NP_001171573
• MIM: 153455
• UniProt ID: P28300