Recombinant Human LRRC32 protein, Fc-tagged
Cat.No. : | LRRC32-396H |
Product Overview : | Recombinant Human LRRC32 protein (His20-Asn627), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | Leucine-rich repeat protein 32 (LRRC32), also known as GARP (glycoprotein A repetitions predominant). LRRC32 expression promotes the acquisition of a Treg phenotype including reduced cellular proliferation, reduced cytokine secretion, and the capacity to suppress the proliferation of naïve T cells. LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Form : | Lyophilized from 0.22 um filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 92.4 kDa. The protein migrates as 106 KDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | 608 |
Endotoxin : | Less than 1.0 EU per ug by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 centigrade to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | LRRC32 |
Official Symbol : | LRRC32 |
Synonyms : | LRRC32; leucine rich repeat containing 32; D11S833E, GARP, glycoprotein A repetitions predominant; leucine-rich repeat-containing protein 32; garpin; glycoprotein A repetitions predominant; GARP; D11S833E |
Gene ID : | 2615 |
mRNA Refseq : | NM_001128922 |
Protein Refseq : | NP_001122394 |
MIM : | 137207 |
UniProt ID : | Q14392 |
Products Types
◆ Recombinant Protein | ||
LRRC32-45H | Active Recombinant Human LRRC32 Protein, His-tagged | +Inquiry |
Lrrc32-3829M | Recombinant Mouse Lrrc32 Protein, Myc/DDK-tagged | +Inquiry |
LRRC32-366H | Recombinant Human LRRC32 Protein, Fc-tagged | +Inquiry |
Lrrc32-1520M | Recombinant Mouse Lrrc32 protein, His & T7-tagged | +Inquiry |
Lrrc32-1521R | Recombinant Rat Lrrc32 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
LRRC32-4635HCL | Recombinant Human LRRC32 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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