Recombinant Human LRRFIP1 Protein (1-314 aa), His-tagged

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Recombinant Human LRRFIP1 Protein (1-314 aa), His-tagged

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Cat.No. : LRRFIP1-634H
Product Overview : Recombinant Human LRRFIP1 Protein (1-314 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Transcription. Protein Description: Partial.
Description : Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Source : E. coli
Species : Human
Tag : His
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 40.1 kDa
Protein length : 1-314 aa
AA Sequence : MTSPAAAQSR EIDCLSPEAQ KLAEARLAAK RAARAEAREI RMKELERQQK EVEERPEKDF TEKGSRNMPG LSAATLASLG GTSSRRGSGD TSISIDTEAS IREIKDSLAE VEEKYKKAMV SNAQLDNEKT NFMYQVDTLK DMLLELEEQL AESRRQYEEK NKEFEREKHA HSILQFQFAE VKEALKQREE MLEKHGIILN SEIATNGETS DTLNNVGYQG PTKMTKEELN ALKSTGDGTL GRASEVEVKN EIVANVGKRE ILHNTEKEQH TEDTVKDCVD IEVFPAGENT EDQKSSEDTA PFLGTLAGAT YEEQSLSTCS LDR
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 [ Homo sapiens ]
Official Symbol : LRRFIP1
Synonyms : LRRFIP1; FLAP 1; FLIIAP1; GCF 2; HUFI 1; TRIP; GCF2; FLAP1; GCF-2; FLAP-1; HUFI-1; MGC10947; MGC119738; MGC119739;
Gene ID : 9208
mRNA Refseq : NM_001137550
Protein Refseq : NP_001131022
MIM : 603256
UniProt ID : Q32MZ4
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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