Recombinant Human LSS Protein, His-tagged

• Cat.No.: LSS-2405H
• Product Overview: Recombinant Human LSS Protein (Asp97-Ile335) with a N-His tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.6 kDa
• Protein length: Asp97-Ile335
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) [ Homo sapiens (human) ]
• Official Symbol: LSS
• Synonyms: LSS; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase); lanosterol synthase; OSC; hOSC; oxidosqualene--lanosterol cyclase; 2,3-epoxysqualene-lanosterol cyclase; 2,3-epoxysqualene--lanosterol cyclase; FLJ25486; FLJ35015; FLJ39450; FLJ46393
• Gene ID: 4047
• mRNA Refseq: NM_001001438
• Protein Refseq: NP_001001438
• MIM: 600909
• UniProt ID: P48449