Recombinant Human M6PR, His-tagged
Cat.No. : | M6PR-182H |
Product Overview : | M6PR, 27-185aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | M6PR is a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. This protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. Recombinant human M6PR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT |
Molecular Mass : | 20.3kDa (182aa) confirmed by MALDI-TOF |
Protein length : | 27-185aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSTEEKTCD LVGEKGKESE KELALVKRLK PLFNKSFEST VGQGSDTYIY IFRVCREAGN HTSGAGLVQI NKSNGKETVV GRLNETHIFN GSNWIMLIYK GGDEYDNHCG KEQRRAVVMI SCNRHTLADN FNPVSEERGK VQDCFYLFEM DSSLACSPEI SH |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/ml (determined by BRADFORD assay) |
Gene Name : | M6PR mannose-6-phosphate receptor (cation dependent) [ Homo sapiens ] |
Official Symbol : | M6PR |
Synonyms : | M6PR; mannose-6-phosphate receptor (cation dependent); cation-dependent mannose-6-phosphate receptor; Mr 46,000 Man6PR; CD Man-6-P receptor; small mannose 6-phosphate receptor; 46-kDa mannose 6-phosphate receptor; SMPR; MPR46; CD-MPR; MPR 46; MPR-46; FLJ32994; |
Gene ID : | 4074 |
mRNA Refseq : | NM_001207024 |
Protein Refseq : | NP_001193953 |
MIM : | 154540 |
UniProt ID : | P20645 |
Chromosome Location : | 12 |
Pathway : | Clathrin derived vesicle budding, organism-specific biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Lysosome Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; |
Function : | mannose binding; mannose transmembrane transporter activity; receptor activity; transmembrane signaling receptor activity; |
Products Types
◆ Recombinant Protein | ||
M6PR-179H | Recombinant Human M6PR Protein, MYC/DDK-tagged | +Inquiry |
M6PR-2689H | Recombinant Human M6PR protein(31-100 aa), C-His-tagged | +Inquiry |
M6pr-3888M | Recombinant Mouse M6pr Protein, Myc/DDK-tagged | +Inquiry |
M6PR-5285M | Recombinant Mouse M6PR Protein, His (Fc)-Avi-tagged | +Inquiry |
M6PR-1335H | Recombinant Human M6PR Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
M6PR-398HCL | Recombinant Human M6PR lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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