Recombinant Human MAPRE3, His-tagged

• Cat.No.: MAPRE3-27027TH
• Product Overview: Recombinant full length Human EB3 (aa 1-281), with N terminal His tag; 301 aa inclusive of tag, 34.1 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 281 amino acids
• Description: The protein encoded by this gene is a member of the RP/EB family of genes.The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene.
• Conjugation: HIS
• Molecular Weight: 34.100kDa inclusive of tags
• Tissue specificity: Predominantly expressed in brain and muscle.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAVNVYSTSV TSENLSRHDM LAWVNDSLHL NYTKIEQLCS GAAYCQFMDM LFPGCVHLRK VKFQAKLEHE YIHNFKVLQA AFKKMGVDKI IPVEKLVKGK FQDNFEFIQW FKKFFDANYD GKDYNPLLAR QGQDVAPPPN PGDQIFNKSK KLIGTAVPQR TSPTGPKNMQ TSGRLSNVAP PCILRKNPPS ARNGGHETDA QILELNQQLV DLKLTVDGLE KERDFYFSKL RDIELICQEH ESENSPVISG IIGILYATEE GFAPPEDDEI EEHQQEDQDE Y
• Sequence Similarities: Belongs to the MAPRE family.Contains 1 CH (calponin-homology) domain.Contains 1 EB1 C-terminal domain.

Gene Information

• Gene Name: MAPRE3 microtubule-associated protein, RP/EB family, member 3 [ Homo sapiens ]
• Official Symbol: MAPRE3
• Synonyms: MAPRE3; microtubule-associated protein, RP/EB family, member 3; microtubule-associated protein RP/EB family member 3; EB3; RP3
• Gene ID: 22924
• mRNA Refseq: NM_012326
• Protein Refseq: NP_036458
• MIM: 605788
• Uniprot ID: Q9UPY8
• Chromosome Location: 2p23.3-p23.1
• Function: microtubule binding; protein binding; small GTPase regulator activity