Recombinant Human MARS, His-tagged

• Cat.No.: MARS-29127TH
• Product Overview: Recombinant fragment, corresponding to amino acids 270-895 of Human MARS with an N terminal His tag. Predicted mwt: 72 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 270-895 a.a.
• Description: This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. The encoded protein is a component of the multi-tRNA synthetase complex and catalyzes the ligation of methionine to tRNA molecules.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 110 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: SALPYVNNVPHLGNIIGCVLSADVFARYSRLRQWNTLYLC GTDEYGTATETKALEEGLTPQEICDKYHIIHADIYRWF NISFDIFGRTTTPQQTKITQDIFQQLLKRGFVLQDTVE QLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDKCGK LINAVELKKPQCKVCRSCPVVQSSQHLFLDLPKLEKRLEE WLGRTLPGSDWTPNAQFITRSWLRDGLKPRCITRDLKW GTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWERW WKNPEQVDLYQFMAKDNVPFHSLVFPCSALGAEDNYTL VSHLIATEYLNYEDGKFSKSRGVGVFGDMAQDTGIPAD IWRFYLLYIRPEGQDSAFSWTDLLLKNNSELLNNLGNFIN RAGMFVSKFFGGYVPEMVLTPDDQRLLAHVTLELQHYH QLLEKVRIRDALRSILTISRHGNQYIQVNEPWKRIKGS EADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQA QLQLPPPACSILLTNFLCTLPAGHQIGTVSPLFQKLENDQIESLRQRFGGGQAKTSPKPAVVETVTTAKPQQIQALMD EVTKQGNIVRELKAQKADKNEVAAEVAKLLDLKKQLAV AEGKPPEAPK

Gene Information

• Gene Name: MARS methionyl-tRNA synthetase [ Homo sapiens ]
• Official Symbol: MARS
• Synonyms: MARS; methionyl-tRNA synthetase; methionyl-tRNA synthetase, cytoplasmic; methionine tRNA ligase 1; cytoplasmic; MetRS
• Gene ID: 4141
• mRNA Refseq: NM_004990
• Protein Refseq: NP_004981
• MIM: 156560
• Uniprot ID: P56192
• Chromosome Location: 12q13
• Pathway: Aminoacyl-tRNA biosynthesis, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, conserved biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, organism-specific biosystem; Aminoacyl-tRNA biosynthesis, eukaryotes, conserved biosystem; Cytosolic tRNA aminoacylation, organism-specific biosystem
• Function: ATP binding; ligase activity; methionine-tRNA ligase activity; nucleotide binding; tRNA binding