Recombinant Human MBNL1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | MBNL1-2139H |
Product Overview : | MBNL1 MS Standard C13 and N15-labeled recombinant protein (NP_997180) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 36.9 kDa |
AA Sequence : | MAVSVTPIRDTKWLTLEVCREFQRG TCSRPDTECKFAHPSKSCQVENGRV IACFDSLKGRCSRENCKYLHPPPHL KTQLEINGRNNLIQQKNMAMLAQQM QLANAMMPGAPLQPVPMFSVAPSLA TNASAAAFNPYLGPVSPSLVPAEIL PTAPMLVTGNPGVPVPAAAAAAAQK LMRTDRLEVCREYQRGNCNRGENDC RFAHPADSTMIDTNDNTVTVCMDYI KGRCSREKCKYFHPPAHLQAKIKAA QYQVNQAAAAQAAATAAAMGIPQAV LPPLPKRPALEKTNGATAVFNTGIF QYQQALANMQLQQHTAFLPPGSILC MTPATSVDTHNICRTSDTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | MBNL1 muscleblind-like splicing regulator 1 [ Homo sapiens (human) ] |
Official Symbol : | MBNL1 |
Synonyms : | MBNL1; muscleblind-like splicing regulator 1; MBNL, muscleblind (Drosophila) like, muscleblind like (Drosophila); muscleblind-like protein 1; EXP; EXP35; EXP40; EXP42; KIAA0428; triplet-expansion RNA-binding protein; MBNL; DKFZp686P06174; |
Gene ID : | 4154 |
mRNA Refseq : | NM_207297 |
Protein Refseq : | NP_997180 |
MIM : | 606516 |
UniProt ID : | Q9NR56 |
Products Types
◆ Recombinant Protein | ||
Mbnl1-3982M | Recombinant Mouse Mbnl1 Protein, Myc/DDK-tagged | +Inquiry |
MBNL1-241H | Recombinant Human MBNL1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
MBNL1-4523Z | Recombinant Zebrafish MBNL1 | +Inquiry |
MBNL1-2739H | Recombinant Human MBNL1, MYC/DDK-tagged | +Inquiry |
MBNL1-524H | Recombinant Human MBNL1 protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
MBNL1-4441HCL | Recombinant Human MBNL1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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