Recombinant Human MCCC2 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human MCCC2 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : MCCC2-189H
Product Overview : MCCC2 MS Standard C13 and N15-labeled recombinant protein (NP_071415) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 61.3 kDa
AA Sequence : MWAVLRLALR PCARASPAGP RAYHGDSVAS LGTQPDLGSA LYQENYKQMK ALVNQLHERV EHIKLGGGEK ARALHISRGK LLPRERIDNL IDPGSPFLEL SQFAGYQLYD NEEVPGGGII TGIGRVSGVE CMIIANDATV KGGAYYPVTV KKQLRAQEIA MQNRLPCIYL VDSGGAYLPR QADVFPDRDH FGRTFYNQAI MSSKNIAQIA VVMGSCTAGG AYVPAMADEN IIVRKQGTIF LAGPPLVKAA TGEEVSAEDL GGADLHCRKS GVSDHWALDD HHALHLTRKV VRNLNYQKKL DVTIEPSEEP LFPADELYGI VGANLKRSFD VREVIARIVD GSRFTEFKAF YGDTLVTGFA RIFGYPVGIV GNNGVLFSES AKKGTHFVQL CCQRNIPLLF LQNITGFMVG REYEAEGIAK DGAKMVAAVA CAQVPKITLI IGGSYGAGNY GMCGRAYSPR FLYIWPNARI SVMGGEQAAN VLATITKDQR AREGKQFSSA DEAALKEPII KKFEEEGNPY YSSARVWDDG IIDPADTRLV LGLSFSAALN APIEKTDFGI FRMTRTRPLE QKLISEEDLA ANDILDYKDD DDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) [ Homo sapiens (human) ]
Official Symbol : MCCC2
Synonyms : MCCC2; methylcrotonoyl-CoA carboxylase 2 (beta); methylcrotonoyl Coenzyme A carboxylase 2 (beta); methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; MCCB; biotin carboxylase; MCCase subunit beta; 3-methylcrotonyl-CoA carboxylase 2; methylcrotonoyl-Coenzyme A carboxylase 2 (beta); 3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta; 3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit; non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase;
Gene ID : 64087
mRNA Refseq : NM_022132
Protein Refseq : NP_071415
MIM : 609014
UniProt ID : Q9HCC0

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